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DNA methylation patterns expose variations in enhancer-chromatin modifications during embryonic stem cell differentiation

In mammals, cellular identity is defined through strict regulation of chromatin modifications and DNA methylation that control gene expression. Methylation of cytosines at CpG sites in the genome is mainly associated with suppression; however, the reason for enhancer-specific methylation is not full...

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Vydáno v:PLoS Genet
Hlavní autoři: Alajem, Adi, Roth, Hava, Ratgauzer, Sofia, Bavli, Danny, Motzik, Alex, Lahav, Shlomtzion, Peled, Itay, Ram, Oren
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062104/
https://ncbi.nlm.nih.gov/pubmed/33844685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009498
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