Chd1 regulates open chromatin and pluripotency of embryonic stem cells

An open chromatin largely devoid of heterochromatin is a hallmark of stem cells, from Planarians to Mammals. It remains unknown whether an open chromatin is necessary for the differentiation potential of stem cells, and what are the molecules that maintain open chromatin in stem cells. Here we show...

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Bibliographische Detailangaben
Hauptverfasser: Gaspar-Maia, Alexandre, Alajem, Adi, Polesso, Fanny, Sridharan, Rupa, Mason, Michael, Heidersbach, Amy, Ramalho-Santos, João, McManus, Michael T., Plath, Kathrin, Meshorer, Eran, Ramalho-Santos, Miguel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891576/
https://ncbi.nlm.nih.gov/pubmed/19587682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08212
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