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EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines

In epithelial cancers, the epidermal growth factor receptor (EGFR) and integrin α6β4 are frequently overexpressed and found to synergistically activate intracellular signaling pathways that promote cell proliferation and migration. In cancer cells, the β4 subunit is phosphorylated at tyrosine residu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: te Molder, Lisa, Kreft, Maaike, Heemskerk, Niels, Schuring, Joyce, de Pereda, Jose M., Wilhelmsen, Kevin, Sonnenberg, Arnoud
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060419/
https://ncbi.nlm.nih.gov/pubmed/33883672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88134-6
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