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PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736

The integrin α6β4, a major component of hemidesmosomes (HDs), stabilizes keratinocyte cell adhesion to the epidermal basement membrane through binding to the cytoskeletal linker protein plectin and association with keratin filaments. Disruption of the α6β4-plectin interaction through phosphorylation...

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Publicado en:PLoS One
Autores principales: te Molder, Lisa, Sonnenberg, Arnoud
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651554/
https://ncbi.nlm.nih.gov/pubmed/26580203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143357
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