Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors

Samankaltaisia teoksia

• Novel 5-Substituted Pyrrolo[2,3-d]pyrimidines as Dual Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase and as Potential Antitumor Agents
  Tekijä: Wang, Yiqiang, et al.
  Julkaistu: (2015)
• Discovery of 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as dual acting inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis: implications of inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to AMPK activation and anti-tumor activity
  Tekijä: Mitchell-Ryan, Shermaine, et al.
  Julkaistu: (2013)
• Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase
  Tekijä: Deis, Siobhan M., et al.
  Julkaistu: (2016)
• Synthesis and Discovery of High Affinity Folate Receptor-Specific Glycinamide Ribonucleotide Formyltransferase Inhibitors With Antitumor Activity
  Tekijä: Deng, Yijun, et al.
  Julkaistu: (2008)
• On the structural and functional modularity of glycinamide ribonucleotide formyltransferases
  Tekijä: Lee, Seung-Goo, et al.
  Julkaistu: (2003)