Activity-dependent conformational transitions of the insulin receptor–related receptor

The insulin receptor (IR), insulin-like growth factor 1 receptor (IGF-1R), and insulin receptor-related receptor (IRR) form a mini family of predimerized receptor-like tyrosine kinases. IR and IGF-1R bind to their peptide agonists triggering metabolic and cell growth responses. In contrast, IRR, des...

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Vydáno v:J Biol Chem
Hlavní autoři: Batishchev, Oleg V., Kuzmina, Natalia V., Mozhaev, Andrey A., Goryashchenko, Alexander S., Mileshina, Ekaterina D., Orsa, Alexander N., Bocharov, Eduard V., Deyev, Igor E., Petrenko, Alexander G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058561/
https://ncbi.nlm.nih.gov/pubmed/33713705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100534
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