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Site-Directed Mutagenesis of the Fibronectin Domains in Insulin Receptor-Related Receptor

The orphan insulin receptor-related receptor (IRR), in contrast to its close homologs, the insulin receptor (IR) and insulin-like growth factor receptor (IGF-IR) can be activated by mildly alkaline extracellular medium. We have previously demonstrated that IRR activation is defined by its extracellu...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Deyev, Igor E., Chachina, Natalia A., Zhevlenev, Egor S., Petrenko, Alexander G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713427/
https://ncbi.nlm.nih.gov/pubmed/29156593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18112461
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