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Structural Determinants of the Insulin Receptor-related Receptor Activation by Alkali
IRR is a member of the insulin receptor (IR) family that does not have any known agonist of a peptide nature but can be activated by mildly alkaline medium and was thus proposed to function as an extracellular pH sensor. IRR activation by alkali is defined by its N-terminal extracellular region. To...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837130/ https://ncbi.nlm.nih.gov/pubmed/24121506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.483172 |
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