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Evaluation of the Effect of (S)-3,4-Dicarboxyphenylglycine as a Metabotropic Glutamate Receptors Subtype 8 Agonist on Thermal Nociception Following Central Neuropathic Pain

STUDY DESIGN: In this study, we decided to change the activity of periaqueductal gray (PAG)'s metabotropic glutamate receptors subtype 8 (mGluR8) by means of its specific agonist, (S)-3,4-dicarboxyphenylglycine (DCPG), and by knock downing it with mGluR8 siRNA. We then evaluated the changes in...

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Опубликовано в: :Asian Spine J
Главные авторы: Hosseini, Marjan, Parviz, Mohsen, Shabanzadeh, Alireza P., Zamani, Elham
Формат: Artigo
Язык:Inglês
Опубликовано: Korean Society of Spine Surgery 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055451/
https://ncbi.nlm.nih.gov/pubmed/32460469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31616/asj.2019.0367
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