Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer’s disease

Neural network dysfunction may play an important role in Alzheimer’s disease (AD). Neuronal circuits vulnerable to AD are also affected in human amyloid precursor protein (hAPP) transgenic mice. hAPP mice with high levels of amyloid-β peptides in the brain develop AD-like abnormalities, including co...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Palop, Jorge J., Chin, Jeannie, Roberson, Erik D., Wang, Jun, Thwin, Myo T., Bien-Ly, Nga, Yoo, Jong, Ho, Kaitlyn O., Yu, Gui-Qiu, Kreitzer, Anatol, Finkbeiner, Steven, Noebels, Jeffrey L., Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055171/
https://ncbi.nlm.nih.gov/pubmed/17785178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.07.025
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