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Quantifying Biomarkers of Cognitive Dysfunction and Neuronal Network Hyperexcitability in Mouse Models of Alzheimer’s Disease: Depletion of Calcium-Dependent Proteins and Inhibitory Hippocampal Remodeling

High levels of Aβ impair neuronal function at least in part by disrupting normal synaptic transmission and causing dysfunction of neural networks. This network dysfunction includes abnormal synchronization of neuronal activity resulting in epileptiform activity. Over time, this aberrant network acti...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Palop, Jorge J., Mucke, Lennart, Roberson, Erik D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153735/
https://ncbi.nlm.nih.gov/pubmed/20967595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-744-0_17
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