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Amyloid-β Induced Neuronal Dysfunction in Alzheimer’s Disease: From Synapses toward Neural Networks

Alzheimer's disease is the most frequent neurodegenerative disorder and the most common cause of dementia in the elderly. Diverse lines of evidence suggest that amyloid-β (Aβ) peptides have a causal role in its pathogenesis, but the underlying mechanisms remain uncertain. Here we discuss recent...

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Detalhes bibliográficos
Main Authors: Palop, Jorge J., Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072750/
https://ncbi.nlm.nih.gov/pubmed/20581818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2583
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