Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer’s disease

Neural network dysfunction may play an important role in Alzheimer’s disease (AD). Neuronal circuits vulnerable to AD are also affected in human amyloid precursor protein (hAPP) transgenic mice. hAPP mice with high levels of amyloid-β peptides in the brain develop AD-like abnormalities, including co...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuron
Päätekijät: Palop, Jorge J., Chin, Jeannie, Roberson, Erik D., Wang, Jun, Thwin, Myo T., Bien-Ly, Nga, Yoo, Jong, Ho, Kaitlyn O., Yu, Gui-Qiu, Kreitzer, Anatol, Finkbeiner, Steven, Noebels, Jeffrey L., Mucke, Lennart
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055171/
https://ncbi.nlm.nih.gov/pubmed/17785178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.07.025
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