Changes in NAD and Lipid Metabolism Drive Acidosis-Induced Acute Kidney Injury

BACKGROUND: The kidney plays an important role in maintaining normal blood pH. Metabolic acidosis (MA) upregulates the pathway that mitochondria in the proximal tubule (PT) use to produce ammonia and bicarbonate from glutamine, and is associated with AKI. However, the extent to which MA causes AKI,...

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Detaylı Bibliyografya
Yayımlandı:J Am Soc Nephrol
Asıl Yazarlar: Bugarski, Milica, Ghazi, Susan, Polesel, Marcello, Martins, Joana R., Hall, Andrew M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2021
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054907/
https://ncbi.nlm.nih.gov/pubmed/33478973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020071003
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