Combined Structural and Functional Imaging of the Kidney Reveals Major Axial Differences in Proximal Tubule Endocytosis

BACKGROUND: The kidney proximal convoluted tubule (PCT) reabsorbs filtered macromolecules via receptor-mediated endocytosis (RME) or nonspecific fluid phase endocytosis (FPE); endocytosis is also an entry route for disease-causing toxins. PCT cells express the protein ligand receptor megalin and hav...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Schuh, Claus D., Polesel, Marcello, Platonova, Evgenia, Haenni, Dominik, Gassama, Alkaly, Tokonami, Natsuko, Ghazi, Susan, Bugarski, Milica, Devuyst, Olivier, Ziegler, Urs, Hall, Andrew M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2018
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218873/
https://ncbi.nlm.nih.gov/pubmed/30301861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018050522
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