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A Chemical Signature for Cytidine Acetylation in RNA
N4-acetylcytidine (ac4C) is a highly conserved modified RNA nucleobase whose formation is catalyzed by the disease-associated N-acetyltransferase 10 (NAT10). Here we report a sensitive chemical method to localize ac4C in RNA. Specifically, we characterize the susceptibility of ac4C to borohydride-ba...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8054311/ https://ncbi.nlm.nih.gov/pubmed/30252461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b06636 |
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