A carregar...
Systematic in vitro specificity profiling reveals nicking defects in natural and engineered CRISPR–Cas9 variants
Cas9 is an RNA-guided endonuclease in the bacterial CRISPR–Cas immune system and a popular tool for genome editing. The commonly used Streptococcus pyogenes Cas9 (SpCas9) is relatively non-specific and prone to off-target genome editing. Other Cas9 orthologs and engineered variants of SpCas9 have be...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8053117/ https://ncbi.nlm.nih.gov/pubmed/33744974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab163 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|