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Enzymatic anti-CRISPRs improve the bacteriophage arsenal
Bacteriophage-encoded anti-CRISPR (Acr) proteins have previously been thought to inhibit CRISPR-mediated immunity by acting as physical barriers against DNA binding or cleavage. Two new studies report that recently discovered type V Acr proteins use enzymatic activities to shut down the Cas12a endon...
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| 發表在: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6643262/ https://ncbi.nlm.nih.gov/pubmed/30936525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0210-5 |
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