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The revolution continues: Newly discovered systems expand the CRISPR-Cas toolkit

CRISPR–Cas systems defend prokaryotes against bacteriophages and mobile genetic elements and serve as the basis for revolutionary tools for genetic engineering. Class 2 CRISPR–Cas systems use single Cas endonucleases paired with guide RNAs to cleave complementary nucleic acid targets, enabling progr...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Murugan, Karthik, Babu, Kesavan, Sundaresan, Ramya, Rajan, Rakhi, Sashital, Dipali G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683099/
https://ncbi.nlm.nih.gov/pubmed/28985502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.007
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