Synthesis and evaluation of resveratrol derivatives as fetal hemoglobin inducers

Resveratrol (RVT) derivatives (10a-i) were designed, synthesized, and evaluated for their potential as gamma-globin inducers in treating Sickle Cell Disease (SCD) symptoms. All compounds were able to release NO at different levels ranging from 0–26.3%, while RVT did not demonstrate this effect. In v...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioorg Chem
Egile Nagusiak: Bosquesi, Priscila Longhin, Melchior, Aylime Castanho Bolognesi, Pavan, Aline Renata, Lanaro, Carolina, de Souza, Cristiane Maria, Rusinova, Radda, Chelucci, Rafael Consolin, Barbieri, Karina Pereira, Fernandes, Guilherme Felipe dos Santos, Carlos, Iracilda Zepone, Andersen, Olaf Sparre, Costa, Fernando Ferreira, Dos Santos, Jean Leandro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052979/
https://ncbi.nlm.nih.gov/pubmed/32450391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2020.103948
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak