Loading...

Role of Gly197 in the structure and function of protein C

We previously demonstrated that heterozygous Gly197 to Arg mutation in PROC is associated with venous thrombosis due to the mutation abrogating both zymogenic and enzymatic activities of protein C and activated protein C (APC). In this study, we investigated the role of Gly197 on the structure and f...

Full description

Saved in:
Bibliographic Details
Published in:Biochim Biophys Acta Gen Subj
Main Authors: Lu, Yeling, Biswas, Indranil, Villoutreix, Bruno O., Rezaie, Alireza R.
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052293/
https://ncbi.nlm.nih.gov/pubmed/33722640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2021.129892
Tags: Add Tag
No Tags, Be the first to tag this record!