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Role of Gly197 in the structure and function of protein C
We previously demonstrated that heterozygous Gly197 to Arg mutation in PROC is associated with venous thrombosis due to the mutation abrogating both zymogenic and enzymatic activities of protein C and activated protein C (APC). In this study, we investigated the role of Gly197 on the structure and f...
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| Publié dans: | Biochim Biophys Acta Gen Subj |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8052293/ https://ncbi.nlm.nih.gov/pubmed/33722640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2021.129892 |
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