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Thr90Ser mutation in antithrombin is associated with recurrent thrombosis in a heterozygous carrier

Antithrombin (AT) is a serine protease inhibitor that regulates the activity of coagulation proteases of both intrinsic and extrinsic pathways. We identified an AT-deficient patient with a heterozygous Thr90Ser (T90S) mutation who experiences recurrent venous thrombosis. To understand the molecular...

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Publicat a:Thromb Haemost
Autors principals: Lu, Yeling, Villoutreix, Bruno O., Biswas, Indranil, Ding, Qiulan, Wang, Xuefeng, Rezaie, Alireza R.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444675/
https://ncbi.nlm.nih.gov/pubmed/32422680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0040-1710590
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