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Loxhd1 Mutations Cause Mechanotransduction Defects in Cochlear Hair Cells

Sound detection happens in the inner ear via the mechanical deflection of the hair bundle of cochlear hair cells. The hair bundle is an apical specialization consisting of actin-filled membrane protrusions (called stereocilia) connected by tip links (TLs) that transfer the deflection force to gate t...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Trouillet, Alix, Miller, Katharine K., George, Shefin Sam, Wang, Pei, Ali, Noor-E-Seher, Ricci, Anthony, Grillet, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051682/
https://ncbi.nlm.nih.gov/pubmed/33707295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0975-20.2021
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