Harmonin mutations cause mechanotransduction defects in cochlear hair cells

In hair cells, mechanotransduction channels are gated by tip links, the extracellular filaments that consist of cadherin 23 (CDH23) and protocadherin 15 (PCDH15) and connect the stereocilia of each hair cell. However, which molecules mediate cadherin function at tip links is not known. Here we show...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Grillet, Nicolas, Xiong, Wei, Reynolds, Anna, Kazmierczak, Piotr, Sato, Takashi, Lillo, Concepcion, Dumont, Rachel A., Hintermann, Edith, Sczaniecka, Anna, Schwander, Martin, Williams, David, Kachar, Bechara, Gillespie, Peter G., Müller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691393/
https://ncbi.nlm.nih.gov/pubmed/19447093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.04.006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados