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TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells

Hair cells are the mechanosensory cells of the inner ear. Mechanotransduction channels in hair cells are gated by tip links. The molecules that connect tip links to transduction channels are not known. Here we show that the transmembrane protein TMIE forms a ternary complex with the tip-link compone...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Zhao, Bo, Wu, Zizhen, Grillet, Nicolas, Yan, Linxuan, Xiong, Wei, Harkins-Perry, Sarah, Müller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258123/
https://ncbi.nlm.nih.gov/pubmed/25467981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.10.041
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