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TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells

Hair cells are the mechanosensory cells of the inner ear. Mechanotransduction channels in hair cells are gated by tip links. The molecules that connect tip links to transduction channels are not known. Here we show that the transmembrane protein TMIE forms a ternary complex with the tip-link compone...

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Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Zhao, Bo, Wu, Zizhen, Grillet, Nicolas, Yan, Linxuan, Xiong, Wei, Harkins-Perry, Sarah, Müller, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258123/
https://ncbi.nlm.nih.gov/pubmed/25467981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.10.041
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