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The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells
Hair cells of the cochlea are mechanosensors for the perception of sound. Mutations in the LRTOMT gene, which encodes a protein with homology to the catecholamine methyltransferase COMT that is linked to schizophrenia, cause deafness. Here, we show that Tomt/Comt2, the murine ortholog of LRTOMT, has...
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| Опубликовано в: : | eLife |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications, Ltd
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5462538/ https://ncbi.nlm.nih.gov/pubmed/28504928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24318 |
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