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ATM and ATR activation through crosstalk between DNA damage response pathways

Cells losing the ability to self-regulate in response to damage is a hallmark of cancer. When a cell encounters damage, regulatory pathways estimate the severity of damage and promote repair, cell cycle arrest, or apoptosis. This decision-making process would be remarkable if it were based on the to...

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Publicat a:Bull Math Biol
Autors principals: Fedak, Elizabeth A., Adler, Frederick R., Abegglen, Lisa M., Schiffman, Joshua D.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051223/
https://ncbi.nlm.nih.gov/pubmed/33704589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-021-00868-6
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