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Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress

To maintain genome stability, cells have evolved various DNA repair pathways to deal with oxidative DNA damage. DNA damage response (DDR) pathways, including ATM-Chk2 and ATR-Chk1 checkpoints, are also activated in oxidative stress to coordinate DNA repair, cell cycle progression, transcription, apo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Yan, Shan, Sorrell, Melanie, Berman, Zachary
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Basel 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176976/
https://ncbi.nlm.nih.gov/pubmed/24947324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1666-4
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