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Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress
To maintain genome stability, cells have evolved various DNA repair pathways to deal with oxidative DNA damage. DNA damage response (DDR) pathways, including ATM-Chk2 and ATR-Chk1 checkpoints, are also activated in oxidative stress to coordinate DNA repair, cell cycle progression, transcription, apo...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Basel
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176976/ https://ncbi.nlm.nih.gov/pubmed/24947324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1666-4 |
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