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Retroviral prototype foamy virus intasome binding to a nucleosome target does not determine integration efficiency
Retroviral integrases must navigate host DNA packaged as chromatin during integration of the viral genome. Prototype foamy virus (PFV) integrase (IN) forms a tetramer bound to two viral DNA (vDNA) ends in a complex termed an intasome. PFV IN consists of four domains: the amino terminal extension dom...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Biol Chem |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8050864/ https://ncbi.nlm.nih.gov/pubmed/33744295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100550 |
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