Retroviral prototype foamy virus intasome binding to a nucleosome target does not determine integration efficiency

Retroviral integrases must navigate host DNA packaged as chromatin during integration of the viral genome. Prototype foamy virus (PFV) integrase (IN) forms a tetramer bound to two viral DNA (vDNA) ends in a complex termed an intasome. PFV IN consists of four domains: the amino terminal extension dom...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kotlar, Randi M., Jones, Nathan D., Senavirathne, Gayan, Gardner, Anne M., Messer, Ryan K., Tan, Yow Yong, Rabe, Anthony J., Fishel, Richard, Yoder, Kristine E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050864/
https://ncbi.nlm.nih.gov/pubmed/33744295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100550
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados