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Nucleosome DNA unwrapping does not affect prototype foamy virus integration efficiency or site selection
Eukaryotic DNA binding proteins must access genomic DNA that is packaged into chromatin in vivo. During a productive infection, retroviral integrases (IN) must similarly interact with chromatin to integrate the viral cDNA genome. Here we examine the role of nucleosome DNA unwrapping in the retrovira...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6415784/ https://ncbi.nlm.nih.gov/pubmed/30865665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212764 |
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