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Protocol for rapid assessment of the efficacy of novel Wnt inhibitors using zebrafish models
Dysregulation of Wnt signaling is a hallmark of many cancers, and the development of effective, non-toxic small-molecule Wnt inhibitors is desirable. Off-target toxicities of new compounds are typically tested in mouse models, which is both costly and time consuming. Here, we present a rapid and ine...
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| Veröffentlicht in: | STAR Protoc |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8050796/ https://ncbi.nlm.nih.gov/pubmed/33889852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100433 |
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