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Posttranslational and Therapeutic Control of Gasdermin-Mediated Pyroptosis and Inflammation

Pyroptosis is a proinflammatory form of cell death, mediated by membrane pore-forming proteins called gasdermins. Gasdermin pores allow the release of the pro-inflammatory cytokines IL-1β and IL-18 and cause cell swelling and cell lysis leading to release of other intracellular proteins that act as...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Fischer, Fabian A., Chen, Kaiwen W., Bezbradica, Jelena S.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050342/
https://ncbi.nlm.nih.gov/pubmed/33868312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.661162
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