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Switching from Apoptosis to Pyroptosis: Gasdermin-Elicited Inflammation and Antitumor Immunity

Pyroptosis is a necrotic form of regulated cell death. Gasdermines (GSDMs) are a family of intracellular proteins that execute pyroptosis. While GSDMs are expressed as inactive forms, certain proteases proteolytically activate them. The N-terminal fragments of GSDMs form pores in the plasma membrane...

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Vydáno v:Int J Mol Sci
Hlavní autor: Tsuchiya, Kohsuke
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794676/
https://ncbi.nlm.nih.gov/pubmed/33406603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010426
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