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Gasdermins and their role in immunity and inflammation

The gasdermins are a family of pore-forming proteins recently implicated in the immune response. One of these proteins, gasdermin D (GSDMD), has been identified as the executioner of pyroptosis, an inflammatory form of lytic cell death that is induced upon formation of caspase-1–activating inflammas...

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Bibliographic Details
Published in:J Exp Med
Main Authors: Orning, Pontus, Lien, Egil, Fitzgerald, Katherine A.
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829603/
https://ncbi.nlm.nih.gov/pubmed/31548300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190545
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