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Channelling inflammation: gasdermins in physiology and disease
Gasdermins were recently identified as the mediators of pyroptosis — inflammatory cell death triggered by cytosolic sensing of invasive infection and danger signals. Upon activation, gasdermins form cell membrane pores, which release pro-inflammatory cytokines and alarmins and damage the integrity o...
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| Publicado en: | Nat Rev Drug Discov |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7944254/ https://ncbi.nlm.nih.gov/pubmed/33692549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-021-00154-z |
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