Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

Murine regulatory T (Treg) cells in tissues promote tissue homeostasis and regeneration. We sought to identify features that characterize human Treg cells with these functions in healthy tissues. Single-cell chromatin accessibility profiles of murine and human tissue Treg cells defined a conserved,...

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Publicado no:Immunity
Main Authors: Delacher, Michael, Simon, Malte, Sanderink, Lieke, Hotz-Wagenblatt, Agnes, Wuttke, Marina, Schambeck, Kathrin, Schmidleithner, Lisa, Bittner, Sebastian, Pant, Asmita, Ritter, Uwe, Hehlgans, Thomas, Riegel, Dania, Schneider, Verena, Groeber-Becker, Florian Kai, Eigenberger, Andreas, Gebhard, Claudia, Strieder, Nicholas, Fischer, Alexander, Rehli, Michael, Hoffmann, Petra, Edinger, Matthias, Strowig, Till, Huehn, Jochen, Schmidl, Christian, Werner, Jens M., Prantl, Lukas, Brors, Benedikt, Imbusch, Charles D., Feuerer, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050210/
https://ncbi.nlm.nih.gov/pubmed/33789089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.03.007
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