Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

Murine regulatory T (Treg) cells in tissues promote tissue homeostasis and regeneration. We sought to identify features that characterize human Treg cells with these functions in healthy tissues. Single-cell chromatin accessibility profiles of murine and human tissue Treg cells defined a conserved,...

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Vydáno v:Immunity
Hlavní autoři: Delacher, Michael, Simon, Malte, Sanderink, Lieke, Hotz-Wagenblatt, Agnes, Wuttke, Marina, Schambeck, Kathrin, Schmidleithner, Lisa, Bittner, Sebastian, Pant, Asmita, Ritter, Uwe, Hehlgans, Thomas, Riegel, Dania, Schneider, Verena, Groeber-Becker, Florian Kai, Eigenberger, Andreas, Gebhard, Claudia, Strieder, Nicholas, Fischer, Alexander, Rehli, Michael, Hoffmann, Petra, Edinger, Matthias, Strowig, Till, Huehn, Jochen, Schmidl, Christian, Werner, Jens M., Prantl, Lukas, Brors, Benedikt, Imbusch, Charles D., Feuerer, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050210/
https://ncbi.nlm.nih.gov/pubmed/33789089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.03.007
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