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Identifying structural determinants of product specificity in Leishmania major farnesyl diphosphate synthase

Farnesyl diphosphate synthase (FPPS) is an isoprenoid chain elongation enzyme that catalyzes the sequential condensation of dimethylallyl diphosphate (DMAPP; C(5)) with isopentenyl diphosphate (IPP; C(5)) and the resulting geranyl diphosphate (GPP; C(10)) with another molecule of IPP, eventually pro...

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Detalles Bibliográficos
Publicado en:Biochemistry
Main Authors: Maheshwari, Sweta, Kim, Yu Seon, Aripirala, Srinivas, Murphy, Michael, Amzel, L. Mario, Gabelli, Sandra B.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049779/
https://ncbi.nlm.nih.gov/pubmed/32584028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00432
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