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Identifying structural determinants of product specificity in Leishmania major farnesyl diphosphate synthase

Farnesyl diphosphate synthase (FPPS) is an isoprenoid chain elongation enzyme that catalyzes the sequential condensation of dimethylallyl diphosphate (DMAPP; C(5)) with isopentenyl diphosphate (IPP; C(5)) and the resulting geranyl diphosphate (GPP; C(10)) with another molecule of IPP, eventually pro...

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Publicado en:Biochemistry
Autores principales: Maheshwari, Sweta, Kim, Yu Seon, Aripirala, Srinivas, Murphy, Michael, Amzel, L. Mario, Gabelli, Sandra B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049779/
https://ncbi.nlm.nih.gov/pubmed/32584028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00432
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