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Isomerization of Asp is essential for assembly of amyloid-like fibrils of αA-crystallin-derived peptide
Post-translational modifications are often detected in age-related diseases associated with protein misfolding such as cataracts from aged lenses. One of the major post-translational modifications is the isomerization of aspartate residues (L-isoAsp), which could be non-enzymatically and spontaneous...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8049310/ https://ncbi.nlm.nih.gov/pubmed/33857260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250277 |
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