Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation

Neuronal dysfunction and loss associated with the accumulation of amyloid-β (Aβ) in the form of extracellular amyloid plaques and hyperphosphorylated tau in the form of intraneuronal neurofibrillary tangles represent key features of Alzheimer’s disease (AD). Amyloid plaques found in the brains of AD...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Zatsepina, O. G., Kechko, O. I., Mitkevich, V. A., Kozin, S. A., Yurinskaya, M. M., Vinokurov, M. G., Serebryakova, M. V., Rezvykh, A. P., Evgen’ev, M. B., Makarov, A. A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824883/
https://ncbi.nlm.nih.gov/pubmed/29476081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21815-x
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