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Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation
Neuronal dysfunction and loss associated with the accumulation of amyloid-β (Aβ) in the form of extracellular amyloid plaques and hyperphosphorylated tau in the form of intraneuronal neurofibrillary tangles represent key features of Alzheimer’s disease (AD). Amyloid plaques found in the brains of AD...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5824883/ https://ncbi.nlm.nih.gov/pubmed/29476081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21815-x |
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