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Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks

[Image: see text] A practical access to four new halogen-substituted pyrrole building blocks was realized in two to five synthetic steps from commercially available starting materials. The target compounds were prepared on a 50 mg to 1 g scale, and their conversion to nanomolar inhibitors of bacteri...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Cotman, Andrej Emanuel, Guérin, Thomas, Kovačević, Ivana, Benedetto Tiz, Davide, Durcik, Martina, Fulgheri, Federica, Možina, Štefan, Secci, Daniela, Sterle, Maša, Ilaš, Janez, Zega, Anamarija, Zidar, Nace, Mašič, Lucija Peterlin, Tomašič, Tihomir, Leroux, Frédéric R., Hanquet, Gilles, Kikelj, Danijel
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047689/
https://ncbi.nlm.nih.gov/pubmed/33869952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c00331
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