Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

The discovery of multi-targeting ligands of bacterial enzymes is an important strategy to combat rapidly spreading antimicrobial resistance. Bacterial DNA gyrase and topoisomerase IV are validated targets for the development of antibiotics. They can be inhibited at their catalytic sites or at their...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmaceutics
Egile Nagusiak: Durcik, Martina, Skok, Žiga, Ilaš, Janez, Zidar, Nace, Zega, Anamarija, Szili, Petra Éva, Draskovits, Gábor, Révész, Tamás, Kikelj, Danijel, Nyerges, Akos, Pál, Csaba, Mašič, Lucija Peterlin, Tomašič, Tihomir
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822030/
https://ncbi.nlm.nih.gov/pubmed/33374964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13010006
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