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Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation
The discovery of multi-targeting ligands of bacterial enzymes is an important strategy to combat rapidly spreading antimicrobial resistance. Bacterial DNA gyrase and topoisomerase IV are validated targets for the development of antibiotics. They can be inhibited at their catalytic sites or at their...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Pharmaceutics |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
MDPI
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7822030/ https://ncbi.nlm.nih.gov/pubmed/33374964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13010006 |
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