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New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity
The ATP binding site located on the subunit B of DNA gyrase is an attractive target for the development of new antibacterial agents. In recent decades, several small-molecule inhibitor classes have been discovered but none has so far reached the market. We present here the discovery of a promising n...
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| izdano v: | Eur J Med Chem |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016738/ https://ncbi.nlm.nih.gov/pubmed/29778894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.05.011 |
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