Junction plakoglobin regulates and destabilizes HIF2α to inhibit tumorigenesis of renal cell carcinoma

BACKGROUND: Increased hypoxia‐inducible factor 2α (HIF2α) activation is a common event in clear cell renal cell carcinoma (ccRCC) progression. However, the function and underlying mechanism of HIF2α in ccRCC remains uninvestigated. We conducted this study to access the potential link between junctio...

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Dades bibliogràfiques
Publicat a:Cancer Commun (Lond)
Autors principals: Chen, Ke, Zeng, Jin, Sun, Yi, Ouyang, Wei, Yu, Gan, Zhou, Hui, Zhang, Yangjun, Yao, Weimin, Xiao, Wei, Hu, Junhui, Xing, Jinchun, Xiao, Kefeng, Wu, Lily, Chen, Zhiqiang, Ye, Zhangqun, Xu, Hua
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045910/
https://ncbi.nlm.nih.gov/pubmed/33591636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cac2.12142
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