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Regulation of glucose metabolism by p62/SQSTM1 through HIF1α

The signaling adaptor sequestosome 1 (SQSTM1)/p62 is frequently overexpressed in tumors and plays an important role in the regulation of tumorigenesis. Although great progress has been made, biological roles of p62 and relevant molecular mechanisms responsible for its pro-tumor activity remain large...

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Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Chen, Ke, Zeng, Jin, Xiao, Haibing, Huang, Chunhua, Hu, Junhui, Yao, Weimin, Yu, Gan, Xiao, Wei, Xu, Hua, Ye, Zhangqun
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760374/
https://ncbi.nlm.nih.gov/pubmed/26743088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.178756
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