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Regulation of glucose metabolism by p62/SQSTM1 through HIF1α

The signaling adaptor sequestosome 1 (SQSTM1)/p62 is frequently overexpressed in tumors and plays an important role in the regulation of tumorigenesis. Although great progress has been made, biological roles of p62 and relevant molecular mechanisms responsible for its pro-tumor activity remain large...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Chen, Ke, Zeng, Jin, Xiao, Haibing, Huang, Chunhua, Hu, Junhui, Yao, Weimin, Yu, Gan, Xiao, Wei, Xu, Hua, Ye, Zhangqun
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760374/
https://ncbi.nlm.nih.gov/pubmed/26743088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.178756
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