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p62/SQSTM1-Dependent Autophagy of Lewy Body-Like α-Synuclein Inclusions
α-Synuclein is the main component of Lewy bodies, the intraneuronal inclusion bodies characteristic of Parkinson’s disease. Although α-synuclein accumulation is caused by inhibition of proteasome and autophagy-lysosome, the degradation of α-synuclein inclusions is still unknown. Formation of Lewy bo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534125/ https://ncbi.nlm.nih.gov/pubmed/23300799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052868 |
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