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p62/SQSTM1-Dependent Autophagy of Lewy Body-Like α-Synuclein Inclusions

α-Synuclein is the main component of Lewy bodies, the intraneuronal inclusion bodies characteristic of Parkinson’s disease. Although α-synuclein accumulation is caused by inhibition of proteasome and autophagy-lysosome, the degradation of α-synuclein inclusions is still unknown. Formation of Lewy bo...

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Bibliografski detalji
Glavni autori: Watanabe, Yoshihisa, Tatebe, Harutsugu, Taguchi, Katsutoshi, Endo, Yasuhisa, Tokuda, Takahiko, Mizuno, Toshiki, Nakagawa, Masanori, Tanaka, Masaki
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534125/
https://ncbi.nlm.nih.gov/pubmed/23300799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052868
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